English Encyclopedia is licensed by Wikipedia (GNU). You can make sure yourself by using our Plagiarism Check service, This site is protected by wp-copyrightpro.com. Mean concomitant drug use was 3.2 per patient/year. Contact Us Concomitant medication is combining two or more treatment regimes when treating diseases. The concomitant sensations I received from the mixture of warm blackberry pie and melting vanilla ice cream took me to dessert heaven. Whether concomitant drug abuse leads to an increased number of deaths was scientifically analysed in Sheffield, UK. Pharmaceutical companies continue to collect data on reported side effects of the medications they manufacture long after approval testing is complete. All the papers we provide are written from scratch and are free from plagiarism. Concomitant drugs are two or more drugs used or given at or almost at the same time (one after the other, on the same day, etc.). English thesaurus is mainly derived from The Integral Dictionary (TID). Examples: warfarin: Drugs Metabolized by CYP2D6 First example. Examples of concomitant in a sentence, how to use it. Find out more, an offensive content(racist, pornographic, injurious, etc. Get XML access to reach the best products. Intervention: Monitor for adverse reactions and reduce dosage of Zoloft or other protein-bound drugs as warranted. Carline J. van den Dries. Cathartics and laxatives increase the motility of the intestine or increase the bulk of feces. At end of study only: Check this box if participant took no concomitant medication . If the patient is receiving a "concomitant" medicinal drug (prescribed to the patient by another physician), and the radiologist performing the imaging procedure is unaware of this, potentially harmful side-effects can occur and increase the risk of contrast medium-induced nephropathy (i.e. In the case of diabetes-associated concomitant illnesses, such as hypertension, cardiovascular disease and vascular diseases, they must be addressed along with the treatment for diabetes. If a patient is taking a medication PRN, do not use a separate line for each time the medication is taken, instead report the first and last dates taken. Change the target language to find translations. Use of other drugs in combination with psychostimulants may influence either the acute effects of either drug, or the longer-term risks associated with psychostimulant use. 100 examples: Disorganized attachment in early childhood : meta-analysis of precursors… This type of concomitant use can be used to potentiate the desired effect of the medications, such as in the use of tranquilizers with sedatives. Concomitant drugs is also a term recognized with drug abuse or recreational use of street drugs. ○   Anagrams The term has two contextual uses: as used in medicine or as used in drug abuse. None Medication . ○   Wildcard, crossword The authors wanted to find out whether concomitant drug abuse (i.e. Concomitant drugs Definition from Encyclopedia Dictionaries & Glossaries. Therapeutic concomitant drugs often demonstrate negative side effects when taken in combination, as in the above example. Did You Know? Conversely, street and recreational drugs are also often combined in opposition to the primary effect of each — so as to minimize the unpleasant or undesired side effects — such as the concomitant use of cocaine and alcohol.  |  Concomitant use of drugs affecting the renin-angiotensin system Combination therapy with two drugs affecting the renin-angiotensin system (ACE inhibitors, angiotensin-II receptor antagonists, and aliskiren is not recommended due to an increased risk of hyperkalaemia, hypotension, and renal impairment, compared to use of a single drug. The designation concomitant drugs has two contextual uses: as used in medicine or as used in drug abuse. Confidentiality Guaranteed The wordgames anagrams, crossword, Lettris and Boggle are provided by Memodata. The most common drug combined with others in this type of concomitant drug abuse is alcohol. Drugs that may decrease insulin requirements include alcohol, anabolic steroids, aspirin, fenfluramine and monoamine oxidase inhibitors; there have been isolated reports of decreased insulin requirements with captopril, clofibrate, cyclophosphamide, guanethidine, mebendazole, methandienone and oxytetracycline. For this reason, doctors often ask patients what medications they are regularly taking with every office appointment, and pharmacists carefully monitor patients’ drug regimes. For example, the Phase 1b/IIa study of the biologically active compound which was conducted on patients with active and moderate rheumatoid arthritis (RA) when the study protocol allowed a stable concomitant treatment with low doses of oral corticosteroids, NSAIDs or non-biological disease – modifying antirheumatic drugs (DMARDs): Methotrexatum, Leflunomide, Chloroquine, Sulfasalazine. Concomitant Medications Form STUDY NAME Site Name:_____ Pt_ID:_____ This form is cumulative and may beused to capture concomitant medications of a single participant throughout the study. The concomitant use of Paxil CR with another drug that is highly bound to plasma protein may increase free concentrations of Paxil CR or other tightly-bound drugs in plasma. With a SensagentBox, visitors to your site can access reliable information on over 5 million pages provided by Sensagent.com. Yet, another example of concomitant drugs could be tetracycline antibiotics taken with supplemental calcium, where the calcium is taken just once in the morning and the antibiotic is administered every 6 hours until completed. Get XML access to fix the meaning of your metadata. Over time, this information can reveal combined side effects from concomitant drugs. Lettris is a curious tetris-clone game where all the bricks have the same square shape but different content. For instance, chemotherapy is often cited as a prime example of therapeutic concomitant drugs wher… ○   Boggle. Concomitant drugs: lt;p|>|Concomitant drugs| are two or more |drugs| used or given at or almost at the same time (on... World Heritage Encyclopedia, the aggregation of the largest online encyclopedias available, and the most definitive collection ever assembled. The time frame that constitutes the same time varies according to desired effect of the drug, the half-life of each drug administered, the metabolism of each drug, the excretion of each drug and the side effects of each drug individually and collectively. Certain medications and over the counter preparations may cause worsening of MG symptoms. The treatment of these other diseases has an effect on blood sugar levels, so the patient's usual diabetes treatment may have to be changed. We recruited 1,170 patients (mean age 60.1 years, 56.4% male). The SensagentBox are offered by sensAgent. concomitant definition: 1. something that happens with something else and is connected with it: 2. happening and connected…. Company Information The concomitant use of Zoloft with another drug that is highly bound to plasma protein may increase free concentrations of Zoloft or other tightly-bound drugs in plasma. If a drug abuser ingests or misuses two or more drugs, either at the same time, or almost at the same time, for instance one after the other, or on the same day, etc, this is also called "concomitant drugs". Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 … According to the NIDA, As the name suggests, stimulants increase alertness, attention, and energy, as well as elevate blood pressure, heart rate, and respiration. It is recommended that gastroprotective drugs (i.e. Chemotherapy for cancer applies as an example. misoprostol, proton pump inhibitors or high doses of histamine H2 receptor antagonists) be taken concomitantly to prevent NSAID-induced GI complications among older people. Ad The percentages of potential / possible DI between the DAAs and the concomitant drugs on the CNS were: 2.7% … These substances can be beneficial in many ways and may be used to help individuals with learning or mental disorders become more focused and lead more productive lives. An integral aspect of the information they continue to collect is the other drugs a patient takes in addition to their own medication. However, there are concerns that the rate of concomitant use of gastroprotective drugs in elderly NSAID users is too low. Chemotherapy for cancer applies as an example. Purpose. Remember to tell any doctor or dentist about your MG diagnosis. Privacy policy Ethanol Nicotine ... Concomitant marijuana use may increase the pharmacologic and toxic effects of cocaine. Carline J. van den Dries,1Sander van Doorn,1Patrick Souverein,2Romin Pajouheshnia,2Karel G.M. Most English definitions are provided by WordNet . The time frame that constitutes the same time varies according to desired effect of the drug, the half-life of each drug administered, the metabolism of each drug, the excretion of each drug and the side effects of each drug individually and collectively. Examples: warfarin: Drugs Metabolized by CYP2D6: Clinical Impact: This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Your personal information will stay completely confidential and will not be disclosed to any third party. Tips: browse the semantic fields (see From ideas to words) in two languages to learn more. Both consist of 3 medicinal drugs: a) Leucovorin (= folinic acid = calcium folinate), b) 5-Fluorouracil (= 5-FU), and c) Oxaliplatin. Record all concomitant medications, including therapies given to treat adverse events. For instance, chemotherapy is often cited as a prime example of therapeutic concomitant drugs whereby two or more medications are administered literally at the same time for the sake of the patient’s health. Concomitant definition is - accompanying especially in a subordinate or incidental way. Concomitant drugs refer to two or more drugs or medications taken at the same time. The web service Alexandria is granted from Memodata for the Ebay search. an opiate plus another drug of misuse) leads to an increased number of acute accidental opiate-related deaths. [1], Contrast imaging in medicine is another example. Examples of concomitant in a sentence Because the contractor and decorator agreed to concomitant work schedules in the final stages of construction, the house was ready to show well ahead of time. All rights reserved. The concomitant sensations I received from the mixture of warm blackberry pie and melting vanilla ice cream took me to dessert heaven. Ho… Boggle gives you 3 minutes to find as many words (3 letters or more) as you can in a grid of 16 letters. The Number of Concomitant Drugs and the Safety of Direct Oral Anticoagulants in Routine Care Patients with Atrial Fibrillation. By using our services, you agree to our use of cookies. Concomitant Medications NCI CRF Standards: Round 3. This designation is used when 2 or more medicinal drugs are given either at the same time, or almost at the same time, for instance one after the other, or on the same day, etc. Concomitant drugs refer to two or more drugs or medications taken at the same time. Choose the design that fits your site. In general, radiologists carefully ask their patients about other medicinal drugs they are "concomitantly" taking before the imaging procedure. Graphical extrapolations of historical prevalence of FGM have shown a shift in the practice by gradual decline in infibulations and concomitant rise in clitoridectomies. These 2 chemotherapy protocols are very similar in principle. Wikipedia Dictionaries. See if you can get into the grid Hall of Fame ! Table 3-2: Examples of clinical inhibitors for P450-mediated metabolisms (for concomitant use clinical DDI studies and/or drug labeling) (03/06/2020) Strong inhibitors Moderate inhibitors It is well known that such iodinated contrast media can lead to acute allergies in some patients. In addition to producing side effects when combined, concomitant drugs can also block or slow another drug’s metabolism by interfering with the digestive pathway or excretion by the kidneys or the liver, thereby markedly increasing the blocked drug’s half-life. This is often the case in medicine. Add new content to your site from Sensagent by XML. If the blocked drug remains in its active form, symptoms of an overdose of that medication may develop, despite the patient having taken the drugs exactly as ordered.  |  These are imaging procedures in medicine that are performed after giving the patient an iodinated contrast medium (e.g. Examples thereof include excipients, lubricants, binders and disintegrators for solid preparations; and solvents, solubilizing aids, suspending agents, isotonic agents, buffers and soothing agents for liquid preparations. However, if you don’t like your paper for some reason, you can always receive a refund. You can also try the grid of 16 letters. Moons,1Arno W. Hoes,1Geert-Jan Geersing,1and Hendrika A. van den Ham2. If a drug abuser ingests or misuses two or more drugs, either at the same time or almost at the same time, this is also called "concomitant drugs". Since these 3 medicinal drugs are "concomitant" to each other, such a constellation is called "concomitant drugs". Descriptive statistical analysis. The standard of care (sometimes also called the "gold standard") for the adjuvant treatment of stage III colon cancer is the FOLFOX chemotherapy protocol (used in Europe, Japan, Canada, and Australia) and respectively the FLOX chemotherapy protocol (used in the USA). Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. This is often the case in medicine. Kind Code: A1 . Concomitant use of clinical status; occurrence suspected, established nonsteroidal antiinflammatory drugs (NSAIDs) with or probable in well-controlled studies 3 Interaction causes minor effects; occurrence warfarin is one of the examples for pharmacodynamic suspected, established or probable in interaction. the risk damage to the kidneys). Indication It is important to check with your doctor before starting any new medication including over the counter medications or preparations. The Concomitant Medications module was one of the group of variables included in the third round of the CRF Harmonization and Standardization Initiative. United States Patent Application 20050197376 . Examples of drug-specific factors include their cytotoxic effect on cells, mechanisms of clearance, and concomitant use with other non-chemotherapeutic nephrotoxic agents. The authors showed that at least in the Sheffield area, intravenous (IV) administration of an opiate is the most consistent factor associated with drug abuse deaths. Stimulants are a class of drugs that all cause similar effects on the body and mind. Concomitant definition: Concomitant is used to describe something that happens at the same time as another thing... | Meaning, pronunciation, translations and examples To make squares disappear and save space for other squares you have to assemble English words (left, right, up, down) from the falling squares. different types of contrast X-rays, CTs, MRIs). How to use concomitant in a sentence. Concomitant use of aspirin, nonsteroidal anti-inflammatory drugs (NSAIDS), other antiplatelet drugs, warfarin, and other anticoagulants may add to this risk. Cannabis levels seem to be unaffected by cocaine. The time frame that constitutes the same time varies according to desired effect of the drug, the half-life of each drug administered, the metabolism of each drug, the excretion of each drug and the side effects of each drug individually and collectively. ), http://www.bccancer.bc.ca/HPI/ChemotherapyProtocols/default.htm. The influence of concomitant medications on hepatic and intestinal metabolism becomes more complicated when a drug, including a prodrug, is metabolized to one or more active metabolites. Alternately, a blocked drug may remain unable to reach its potent active metabolite and prove ineffective for the patient at a therapeutically prescribed and administered dosage. Give contextual explanation and translation from your sites ! Learn more. Concomitant drug therapy may alter insulin requirements. They may also can lead to kidney damage. English Wikipedia - The Free Encyclopedia. Concomitant drugs refer to two or more drugs or medications taken at the same time. Concomitant drugs . Letters must be adjacent and longer words score better. Cautionary Drugs. ○   Lettris The English word games are: The co-administration of a concomitant drug of misuse appeared to be a feature rather than a risk factor per se in such deaths.[3]. Intervention: Monitor for adverse reactions and reduce dosage of Paxil CR or other protein-bound drugs as warranted. We do our best to make our customers satisfied with the result. Each square carries a letter. Concomitant illnesses may make it more difficult for the treating physician to determine the diagnosis or treatment of the primary illness. In addition showing how in this case, “the same time” means “same day,” this example illustrates one of the negative effects of drugs taken concomitantly — side effects that occur in combination — as concomitant calcium use decreases the effectiveness of the antibiotics. You can feel safe while using our website. Examples of Concomitant in a sentence Because the contractor and decorator agreed to concomitant work schedules in the final stages of construction, the house was ready to show well ahead of time.  | Last modifications, Copyright © 2012 sensagent Corporation: Online Encyclopedia, Thesaurus, Dictionary definitions and more. Concomitant drugs in medicine. This designation is used when 2 or more medicinal drugs are given either at the same time, or almost at the same time, for instance one after the other, or on the same day, etc. Ro, Cookies help us deliver our services. A windows (pop-into) of information (full-content of Sensagent) triggered by double-clicking any word on your webpage. Often, they monitor the kidney function and the hydration status of their patients during the imaging procedure, especially whenever a concomitant drug (that is harmful to the kidney) is being used.[2]. The common examples are Headache > by profuse urination of Gelsemium, Coryza associated with polyurea of Cal carb, Pain with chilliness of puls, Prolapse and uterine affection which is > ted by crossing legs but with empty all gone sinking feeling in abdomen and less sexual desire of Sepia etc. An opiate plus another drug of misuse ) leads to an increased number of accidental. 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Any third party class of drugs that all cause similar effects on the body and mind,. Common drug combined with others in this type of concomitant drug abuse ( i.e Safety of Direct Oral in... Use with other non-chemotherapeutic nephrotoxic agents of drugs that all cause similar effects on the body and.! Recruited 1,170 patients ( mean age 60.1 years, 56.4 % male ) pharmacologic toxic...: Monitor for adverse reactions and reduce dosage of Paxil CR or other protein-bound drugs as warranted are from. About your MG diagnosis different content in combination, as in the above example your site access! Our use of gastroprotective drugs in elderly NSAID users is too low pharmaceutical companies continue to collect data on side! And concomitant drugs examples free from plagiarism infibulations and concomitant use with other non-chemotherapeutic nephrotoxic agents over-the-counter and... Uses: as used in medicine or as used concomitant drugs examples drug abuse or recreational of. Therapies given to treat adverse events van den Ham2 words ) in two languages learn. The grid Hall of Fame t like your paper for some reason, you agree to use... Patients with Atrial Fibrillation injurious, etc drugs, over-the-counter medicines and natural products mixture of warm blackberry pie melting. Patient an iodinated contrast media can lead to acute allergies in some patients concomitant '' to other! Have shown a shift in the third Round of the information they continue to collect data on side! Paxil CR or other protein-bound drugs as warranted in clitoridectomies subordinate or incidental way male! Shift in the above example often demonstrate negative side effects when taken in combination, as in the Round... Shape but different content site can access reliable information on more than 24,000 prescription,... Side effects when taken in combination, as in the above example contrast medium e.g. A. van den Ham2 scientifically analysed in Sheffield, UK to dessert heaven drugs or medications taken the... Or incidental way their cytotoxic effect on cells, mechanisms of clearance and! Are very similar in principle cause worsening of MG symptoms longer words better! If participant took no concomitant medication collect data on reported side effects when taken in combination as... Contrast media can lead to acute allergies in some patients only and is connected with it: happening... The third Round of the medications they manufacture long after approval testing is complete whether concomitant drug.!, injurious, etc of drugs that all cause similar effects on the body mind... I received from the mixture of warm blackberry pie and melting vanilla ice cream took me to dessert heaven or! An opiate plus another drug of misuse ) leads to an increased number of acute opiate-related... From scratch and are free from plagiarism Zoloft or other protein-bound drugs as warranted and Standardization Initiative and. To dessert heaven be adjacent and longer words score better most common drug combined with others in type. Cause similar effects on the body and mind any word on your.. Time, this information can reveal combined side effects when taken in combination, as in the example. Grid Hall of Fame over time, this information can reveal combined side when., chemotherapy is often cited as a prime example of therapeutic concomitant drugs has two uses! Of street drugs medications, including therapies given to treat adverse events '' to other!